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Ribosomal protein SA pseudogene 64 (RPSAP64) is annotated as a pseudogene of the Ribosomal protein SA (RPSA) gene. Pseudogenes are genomic sequences similar to known genes but lack coding potential due to mutations or truncations. RPSAP64 does not encode a protein and is not involved in cellular processes or pathologies as an active molecule. There is no scientific evidence that RPSAP64 is a molecular target for drugs, nor does it have disease associations, biological functions, or biomarker status. Its presence reflects the evolutionary expansion of the RPSA gene family, which includes numerous processed pseudogenes across mammalian genomes. RPSAP64 is listed in gene databases (NCBI, Ensembl, GeneCards) as a pseudogene and not as a protein-coding gene or a functional therapeutic target. Functionally, only the parent gene RPSA encodes the active 40S ribosomal protein SA, which has roles as a ribosomal protein and laminin receptor, but RPSAP64 does not contribute to these functions. No associations are documented for RPSAP64 with diseases, drug interactions, biological pathways, or therapeutics. This nomenclature is correct for a pseudogene but would be incorrect if interpreted as an actionable therapeutic target.
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