Ribosomal protein SA pseudogene 7 (RPSAP7)

Ribosomal protein SA pseudogene 7 (RPSAP7) is a processed pseudogene of the functional ribosomal protein SA (RPSA) gene, sharing nearly identical sequence and open reading frame, except for a single amino acid change[1][5]. Like other pseudogenes, RPSAP7 does not code for a functional protein in humans and is not believed to be transcribed or translated into a biologically active form under normal circumstances. While pseudogenes can occasionally produce regulatory RNA or rare proteins in some contexts, there is no robust evidence for such a role for RPSAP7. The functional RPSA protein itself is involved in ribosomal structure, cell adhesion (as a laminin receptor), and pathologies such as cancer and prion diseases, but these activities do not pertain to RPSAP7[7][1]. Pseudogenes in general may modulate their parental gene's expression by acting as microRNA decoys or source of regulatory non-coding RNAs, but RPSAP7 has not been shown to directly participate in such mechanisms[6]. In summary, RPSAP7 is a non-coding genetic element and is not classified as a therapeutic target, receptor, enzyme, transporter, or biomarker. It does not have any established protein function, disease role, or pharmacological relevance.

Other names

Laminin receptor 1 pseudogene 7LAMR1P7RPSA_16_1024RPSAP7