ribosomal protein SA pseudogene 71 (RPSAP71)

RPSAP71 (ribosomal protein SA pseudogene 71) is a pseudogene—a nonfunctional DNA sequence similar to the ribosomal protein SA (RPSA) gene[3]. Pseudogenes arise via retrotransposition or duplication of functional genes but generally do not produce functional proteins, lacking either regulatory elements or harboring disabling mutations. RPSA encodes a multifunctional ribosomal protein that also serves as a cell surface laminin receptor involved in processes like cell adhesion, migration, and metastasis[1][5]. However, RPSAP71 does not code for an active protein and has no described biological function, therapeutic relevance, or biomarker status. The RPSA/laminin receptor and its functional gene (RPSA) are well-studied and biologically important, but RPSAP71 is explicitly a pseudogene, not a receptor, enzyme, or druggable target[3]. There is no evidence that RPSAP71 is expressed as a protein or involved in any biological process, disease, or drug interaction. If the intent is to refer to the biologically active RPSA (not RPSAP71), consult entries for "ribosomal protein SA" instead[1][5]. Pseudogenes are cataloged largely as a source of non-coding RNA or genomic structural variation, not as canonical molecular targets. RPSAP71 is not an active receptor, enzyme, or target but a nonfunctional pseudogene related to ribosomal protein SA. No direct biological functions, disease roles, drug interactions, or biomarker status are attributed to RPSAP71 at this time[3]. The entry is marked as incorrect for use as a drug target due to its pseudogene status. For therapeutic or biological study, reference the functional RPSA gene/protein (laminin receptor) instead[1][5].

Other names

RPSAP71