Ribulose-5-phosphate-3-epimerase pseudogene 3 (RPEP3)

RPEP3 (ribulose-5-phosphate-3-epimerase pseudogene 3) is annotated as a *pseudogene* in the human genome, with Gene ID 100420555[3]. Pseudogenes are genomic DNA sequences similar to normal genes but are nonfunctional; they typically arise from gene duplication or retrotransposition and lack the ability to encode functional proteins. Unlike the protein-coding gene RPE (ribulose-5-phosphate 3-epimerase), which is an enzyme involved in the pentose phosphate pathway and Calvin cycle[2][4], RPEP3 does not code for an active enzyme and is not considered a drug target, disease biomarker, or therapeutic agent. There is no evidence for a functional role, disease association, or drug targeting for RPEP3[3]. Key clarifications: - RPEP3 is *not* a protein-coding gene; it is a pseudogene in humans[3]. - There is *no known biological function*, *disease association*, or *therapeutic relevance*. - It should not be confused with "ribulose-5-phosphate 3-epimerase" (abbreviated as RPE), which is a functional enzyme involved in core metabolic pathways[2][4]. - Because pseudogenes are generally non-functional and not involved in therapeutic drug targeting, *is_target* is **false** and *is_incorrect* is **true** for a therapeutic target list. If you need information about the **active enzyme** ("ribulose-5-phosphate 3-epimerase" / RPE), please specify, as that is a biochemically and therapeutically distinct entity[2][4].

Other names

ribulose 5-phosphate 3-epimerase pseudogene 3