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The Rieske Fe-S domain-containing protein (RFESD) is a protein-coding gene product characterized by the presence of a Rieske [2Fe-2S] iron-sulfur domain, which is typically involved in electron transfer through binding 2 iron, 2 sulfur clusters. It is predicted to have oxidoreductase activity and bind [2Fe-2S] clusters, functions that are central to energy metabolism and redox processes in cells. The gene is not currently associated with specific diseases, nor is it a common therapeutic target or biomarker. While other Rieske Fe-S domain proteins have critical roles in respiratory and photosynthetic electron transport chains, the specific physiological and pathological relevance of RFESD in humans remains to be fully elucidated.
None established
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