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The ring finger protein 123 pseudogene (RNF123 pseudogene, ENSG00000283773) is a pseudogene with high homology to the functional RNF123 gene but does not encode a functional protein[1][2]. Pseudogenes like this are generally defined as genomic sequences resembling genes but incapable of producing a functional protein product[2]. Some pseudogenes can produce noncoding RNAs that may regulate gene expression at the RNA level, either through microRNA sponging, RNA interference, or acting as competitive endogenous RNAs[4][6]. However, there is no evidence that ENSG00000283773 serves as a therapeutic target, biomarker, or direct participant in drug action. This entry refers to a pseudogene, not a protein-coding gene, and thus is not considered a therapeutic target under standard classifications. If a functional protein is of interest, refer to the parent gene RNF123 (Ring finger protein 123), not the pseudogene variant.
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