Ring finger protein 4 pseudogene

Ring finger protein 4 pseudogene (ENSG00000227934) is a nonfunctional stretch of DNA in the human genome that resembles the RNF4 gene but does not encode a functional protein product[1][2]. Pseudogenes typically arise from duplication or retrotransposition events but accumulate disabling mutations such as premature stop codons or frame shifts, rendering them unable to produce functional proteins[2]. They are often classified as "junk DNA," although some may be transcribed at low levels, rarely giving rise to regulatory RNA, but there is no evidence of functional or therapeutic roles for the ring finger protein 4 pseudogene[2]. This pseudogene should not be confused with the functional RNF4 gene, which encodes a RING finger E3 ubiquitin ligase with established roles in transcription regulation and disease[6]. If your intention was to reference a therapeutic target, the correct entity would be the Ring finger protein 4 (RNF4), a distinct and functional protein-coding gene[6].

Other names

Ring finger protein 4 pseudogeneRNF4 pseudogeneGC01P231157GC01P231022GC01P231180GC01P231451GC01P231888GC01P232333GC01P232819