RN7SK pseudogene 104 (RN7SKP104)

RN7SK pseudogene 104 (RN7SKP104), also known as "RNA, 7SK small nuclear pseudogene 104," refers to a **pseudogene** related to the functional 7SK small nuclear RNA (RN7SK). As a pseudogene, it is generally considered a non-functional genomic element derived from a functional gene, in this case, RN7SK[4]. **RN7SK pseudogene 104** is a pseudogene—an inactive genomic sequence that shares homology with the functional RN7SK gene, which encodes a small nuclear RNA (snRNA) involved in the regulation of transcription elongation by RNA polymerase II[4]. The active 7SK RNA functions as a scaffold in a ribonucleoprotein complex that regulates P-TEFb, thereby controlling RNA polymerase II's transition into productive elongation during transcription[1][2][5]. However, RN7SKP104 itself lacks evidence for expression or function and is not implicated as a therapeutic target, receptor, or molecule with biological, disease, or pharmacological relevance[4]. **Key clarifications:** - **Pseudogenes** like RN7SKP104 do not produce functional RNA or protein, and there is no evidence linking this specific pseudogene to any therapeutic targeting, biological process, or disease involvement[4]. - All functional and biological significance in the 7SK family is attributed to the parent gene RN7SK, not RN7SKP104[1][2][5]. RN7SKP104 should not be confused with RN7SK, an active non-coding snRNA with pivotal roles in transcription regulation and cell cycle control, which is considered biologically relevant but not a typical drug target[1][2][5].

Other names

RNA, 7SK small nuclear pseudogene 104RN7SKP104