RN7SK pseudogene 114 (RN7SKP114)

RN7SK pseudogene 114 is a human pseudogene located on chromosome 9. It is related by sequence to the functionally characterized 7SK small nuclear RNA (RN7SK), but as a pseudogene, RN7SKP114 does not encode a functional transcript or protein[2][3]. The functional RN7SK RNA participates in regulation of transcription elongation by modulating the positive transcription elongation factor P-TEFb in cells[1]. Pseudogenes such as RN7SKP114 typically arise through duplication or retrotransposition events and are generally non-functional remnants in the genome, with no known roles in normal physiology or disease[2][3]. No evidence supports the therapeutic targeting of RN7SKP114, and it is not considered a drug target.\n\nIf detailed functional or clinical data are required, information should be sought for the functional gene "RN7SK" (not RN7SKP114), which plays a regulatory role in transcription[1][5]. RN7SKP114 itself is not a therapeutic target and does not encode any receptor, enzyme, transporter, or similar druggable entity[2][3].

Other names

RNA, 7SK small nuclear pseudogene 114RN7SKP114