Target intelligence / Profile preview

RN7SK pseudogene 118 (RN7SKP118)

Target
RN7SKP118
Molecular classification
Pseudogene, Non-coding RNA pseudogene, Other
01

Overview

RN7SK pseudogene 118 (RN7SKP118) is a pseudogene related to the functional small nuclear noncoding RNA 7SK (RN7SK), which itself is known to regulate RNA polymerase II transcriptional elongation as part of the 7SK small nuclear ribonucleoprotein (snRNP) complex[1][2]. Functional 7SK RNA acts as a regulator of gene expression, particularly through modulation of P-TEFb activity, chromatin accessibility, and splicing, especially in neuronal and skin tissues[1][2]. However, the RN7SKP118 entity itself is a \"pseudogene\"—a non-functional genomic segment resulting from duplication or retrotransposition and does not code for a functional RNA or protein product, nor is it recognized as a receptor, enzyme, transporter, or therapeutically relevant molecular target[1][2]. No data supports any specific biological or disease-related function for RN7SKP118.

Other names
RN7SKP118RNA, 7SK small nuclear pseudogene 118
02

Mechanism of action

Not applicable; no approved or experimental drugs known to interact with pseudogenes of RN7SK.

03

Biological functions

None known for this specific pseudogene; functional 7SK RNA (not the pseudogene) regulates transcriptional elongation and splicing via binding to P-TEFb and hnRNPs in neuronal and non-neuronal tissues
04

Disease associations

None known for this specific pseudogene; functional 7SK RNA has roles in neuronal development and may be involved in disease through transcriptional regulation, but pseudogenes typically lack such direct roles

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