Target intelligence / Profile preview

RN7SK pseudogene 139 (RN7SKP139)

Target
RN7SKP139
Molecular classification
Pseudogene, non-coding RNA pseudogene
01

Overview

RN7SK pseudogene 139 is a human pseudogene annotated as RN7SKP139. It is part of a large family of 7SK small nuclear RNA (snRNA) pseudogenes, which are non-protein-coding RNA sequences sharing sequence similarity with the functional RN7SK gene. Pseudogenes like RN7SKP139 usually do not produce functional RNA or protein products due to mutations or lack of regulatory elements. There are no known biological functions, molecular interactions, drug targets, therapeutic implications, or disease associations for this particular pseudogene[1]. The functional gene, *RN7SK*, encodes the 7SK snRNA, a well-studied regulator of transcription elongation in human cells via the sequestration and modulation of P-TEFb and related complexes[2][5][6]. However, *RN7SKP139* as a *pseudogene* does not contribute to these functions and lacks evidence for expression or functional activity[1][4]. Thus, *RN7SKP139* should not be considered a therapeutic target or functional receptor/enzyme.

02

Mechanism of action

None

03

Biological functions

None known; as a pseudogene, it is generally presumed non-functional
04

Disease associations

None established; there is no evidence for a disease association for this pseudogene

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