RN7SK pseudogene 153 (RN7SKP153)

RN7SK pseudogene 153 (RN7SKP153) is a processed pseudogene of the functional gene encoding 7SK small nuclear RNA (RN7SK). While the functional 7SK snRNA is a key non-coding RNA involved in regulation of RNA polymerase II transcription and gene expression by controlling P-TEFb activity[1][6][2][4], pseudogenes such as RN7SKP153 do not produce a functional RNA product and are not known to have direct biological or disease-associated functions. RN7SKP153 is cataloged in genomic databases as a non-coding, likely non-functional RNA locus, with no evidence as a therapeutic target, biomarker, or disease driver[3]. There is no established or inferred interaction with drugs, nor is it associated with safety concerns or therapeutic value. The pseudogene exists due to historical genomic duplication or retrotransposition of the RN7SK locus.

Other names

RNA, 7SK small nuclear pseudogene 153RN7SKP153