RN7SK pseudogene 172 (RN7SKP172)

RN7SK pseudogene 172 is a predicted non-functional genomic sequence related to the 7SK small nuclear RNA gene (RN7SK), designated as a pseudogene because it does not encode an active small nuclear RNA and has no known biological or therapeutic role. In contrast, the functional 7SK RNA is a non-coding RNA that regulates gene transcription by sequestering and inactivating the positive transcription elongation factor b (P-TEFb)[1][2][3][4][5]. Dysregulation of 7SK RNA (not its pseudogenes) has been implicated in human disease, including cancer and heart disorders[2][4]. RN7SKP172 has no established role, function, or relevance as a drug target. If information for RN7SKP172 is sought for drug discovery or disease association, the canonical RN7SK gene and its product, 7SK snRNA, should be considered instead[1][2][4].

Other names

RN7SKP172RNA, 7SK small nuclear pseudogene 1727SK pseudogene 172