Target intelligence / Profile preview

RN7SK pseudogene 19 (RN7SKP19)

Target
RN7SKP19
Molecular classification
Other (Pseudogene)
01

Overview

RN7SK pseudogene 19 (RN7SKP19) is a pseudogene of the 7SK small nuclear RNA gene (RN7SK). Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they typically do not produce a functional RNA or protein product. The parent gene, RN7SK, codes for a small nuclear RNA that regulates transcription elongation by RNA polymerase II, but RN7SKP19 itself is not believed to be transcribed into a functional RNA nor to participate in biological processes, disease, or drug interactions[2][3][4][5]. The RN7SK gene encodes a non-coding RNA involved in negative regulation of transcription elongation by binding and sequestering the CDK9/cyclin T complex, but RN7SKP19 is a pseudogene and does not perform this function[3][5]. Pseudogenes like RN7SKP19 are common in the genome; most are unexpressed and non-functional copies of genes[1][2]. There are no known associations with diseases, drugs, or diagnostic biomarkers for this pseudogene[2][3]. This gene is not considered a valid therapeutic target or relevant for functional molecular classification. Any entry listing RN7SKP19 as a druggable target is likely incorrect or misinformed[2][3].

Other names
RNA, 7SK small nuclear pseudogene 19RN7SKP19

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