RN7SK pseudogene 192 (RN7SKP192)

RN7SK pseudogene 192 (RN7SKP192) is a human genomic locus classified as a pseudogene, related in sequence to the functional RN7SK gene, which encodes the 7SK small nuclear RNA—a non-coding RNA involved in the regulation of transcriptional elongation through interaction with the positive transcription elongation factor b (P-TEFb)[3][2]. As a pseudogene, RN7SKP192 does not produce a functional RNA or protein product and has no established biological function, disease association, or therapeutic relevance[3][4]. The numbering "192" indicates it is one of many pseudogenized copies identified in the human genome, with no evidence of expression or function. The functional parent gene, RN7SK, is involved in regulation of transcription elongation by RNA polymerase II[2], but RN7SKP192 itself is an inactive copy ("pseudogene"), part of a large family of similar non-coding RNA gene remnants in the human genome[1][3]. RN7SKP192 has been assigned identifiers by major genetic databases, such as HGNC: 45916, NCBI Gene: 106480892, and Ensembl: ENSG00000223223[3][4]. RN7SKP192 is a pseudogene locus of the 7SK small nuclear RNA gene family, does not encode a functional product, and is not considered a therapeutic or biological target.

Other names

RN7SKP192RNA, 7SK small nuclear pseudogene 192