RN7SK pseudogene 259 (RN7SKP259)

RN7SK pseudogene 259 (RN7SKP259) is annotated as a non-coding RNA pseudogene found on chromosome 11 (chr11:57451690-57452022, hg38)[2]. Pseudogenes like RN7SKP259 are typically defective copies of functional RNA genes—in this case, the 7SK small nuclear RNA gene. The functional 7SK RNA is an essential component of the 7SK ribonucleoprotein complex, which regulates RNA polymerase II transcription elongation by sequestering positive transcription elongation factor b (P-TEFb)[1]. However, RN7SKP259 lacks evidence of transcription or functional RNA production, does not participate in ribonucleoprotein complexes, and has no recorded biological or disease role.

Other names

RNA, 7SK small nuclear pseudogene 259RN7SKP259