RN7SK pseudogene 8 (RN7SKP8)

RN7SK pseudogene 8 (RN7SKP8) is a genomic sequence similar to the functional RN7SK gene, which codes for 7SK small nuclear RNA, a non-coding RNA involved in regulating transcription elongation by interacting with positive transcription elongation factor b (P-TEFb) and contributing to the control of gene expression[3][4]. Unlike RN7SK, RN7SKP8 is classified as a pseudogene, meaning it is a non-functional copy resulting from gene duplication or retrotransposition and does not produce a functional lncRNA or protein[4]. There is no specific evidence in the literature that RN7SKP8 itself plays a significant regulatory or therapeutic role. Most scientific knowledge and drug development focus on functional lncRNAs like RN7SK, which have roles in transcriptional regulation and immune cell biology, but not on their pseudogenes or RN7SKP8 specifically[1][2][3][4]. RN7SKP8 should not be considered a canonical molecular target for therapeutic intervention.

Other names

RN7SKP8RNA, 7SK small nuclear pseudogene 87SK small nuclear RNA pseudogene 8