RN7SK pseudogene 80 (RN7SKP80)

RN7SK pseudogene 80 (RN7SKP80) is a nonfunctional pseudogene related to the 7SK small nuclear RNA (snRNA). The functional 7SK snRNA is a highly abundant and conserved noncoding RNA that plays a crucial regulatory role by sequestering and inhibiting the positive transcription elongation factor P-TEFb, thus controlling the elongation phase of RNA polymerase II-dependent transcription[1][2][3]. The pseudogene variant, however, does not encode the functional RNA, lacks biological activity, is not a therapeutic target, and is not known to interact with pharmaceuticals or have disease associations.

Other names

RN7SKP80RNA, 7SK small nuclear pseudogene 80

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