RN7SK pseudogene 85 (RN7SKP85)

**RN7SK pseudogene 85** is a *non-functional pseudogene* related to the highly conserved 7SK small nuclear RNA (7SK RNA) locus[1][7]. The parent gene, RN7SK, encodes a small nuclear RNA component of the 7SK small nuclear ribonucleoprotein (snRNP), which regulates transcriptional elongation in eukaryotic cells by modulating the activity of positive transcription elongation factor b (P-TEFb)[2][4][6]. However, RN7SKP85 does **not produce a functional RNA** and does not possess regulatory or enzymatic activity. It is one of many processed pseudogenes derived from the functional 7SK RNA gene described in the human genome[7]. **Key context**: - **RN7SKP85** is not the same as the functional **RN7SK** gene, which is structurally and functionally important in gene regulation. - There is *no evidence* associating RN7SKP85 with protein coding, cellular pathways, or diseases[1][7]. - One study confirmed 85 RN7SK pseudogenes in the human genome, none of which are believed to encode a functional RNA or have any physiologically relevant function[7]. **In summary:** RN7SK pseudogene 85 is a non-functional genomic element derived from the 7SK small nuclear RNA locus and does not serve as a therapeutic target, functional regulatory element, or disease biomarker in humans[1][7].

Other names

RNA, 7SK small nuclear pseudogene 85RN7SKP85[1]