RNA, 7SL, cytoplasmic 173, pseudogene (RN7SL173P)

RN7SL173P is a human genomic pseudogene derived from the 7SL RNA gene, which is a component of the signal recognition particle (SRP) complex. Unlike the ~4 functional 7SL RNA genes, RN7SL173P and hundreds of similar copies in the human genome are non-functional, typically due to truncations or accumulated mutations, and do not produce functional RNA for SRP assembly. 7SL RNA is vital for cotranslational targeting of proteins to the endoplasmic reticulum, but the pseudogenes (like RN7SL173P) do not contribute to this function and are considered genomic fossils, though the possibility for some transcript-level regulatory activity exists in principle as seen with other pseudogenes.

Other names

RN7SL173P7SL RNA pseudogene 1737SL RNA pseudogeneRNA 7SL pseudogene7SL RNA-like pseudogene