Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 204, pseudogene (RN7SL204P)

Target
RN7SL204P
Molecular classification
Pseudogene, Non-coding RNA locus
01

Overview

RN7SL204P is a pseudogene locus derived from the 7SL RNA gene, which encodes the RNA backbone of the signal recognition particle, a ribonucleoprotein complex critical for protein targeting to the endoplasmic reticulum in eukaryotic cells[1][3][5]. In the human genome, hundreds of distinct 7SL RNA-like pseudogenes are present—these arise from the reverse integration of RNA back into DNA but generally do not produce functional RNA nor protein[5]. While some pseudogenes can influence the expression of their parent genes or act as regulatory RNAs, there is no evidence RN7SL204P is expressed or functional, nor is it associated with any disease or clinical biomarker utility[6]. Therefore, RN7SL204P is not considered a therapeutic target.

Other names
RN7SL204PRNA, 7SL, cytoplasmic 204, pseudogene
02

Mechanism of action

Not applicable. As a noncoding pseudogene, there are no drugs nor mechanisms known to target it.

03

Biological functions

None specific for the pseudogene; Parent 7SL RNA is a functional scaffold for SRP in protein targeting and translocationPseudogenes themselves may, in some cases, influence gene expression through regulatory RNA or as competitive endogenous RNA, but there is no evidence this specific pseudogene does
04

Disease associations

None definitive; generally not associated with diseases individually, but some pseudogenes can act as disease modifiers or biomarkers in specific contexts, primarily through regulatory RNA effectsNo evidence links RN7SL204P to disease directly.
05

Safety considerations

None. Pseudogenes do not produce proteins and are not direct therapeutic targets.
06

Interacting drugs

None
07

Biomarkers

None identified for RN7SL204P.

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