RNA, 7SL, cytoplasmic 430, pseudogene (RN7SL430P)

RNA, 7SL, cytoplasmic 430, pseudogene (RN7SL430P) is a human pseudogene derived from the 7SL RNA sequence, which primarily serves as the RNA component of the signal recognition particle (SRP) in protein targeting to membranes[1][3][6]. Unlike the functional 7SL RNA, RN7SL430P does not encode a protein or an active RNA with known cellular activity; it is a non-coding genomic sequence formed by reverse transcription and integration, resulting in a truncated, nonfunctional RNA copy[1][3]. Human DNA contains hundreds of such 7SL RNA-like pseudogenes, most of which are not expressed or functional[3][4]. While other pseudogenes have been shown to act as regulators of gene expression by acting as “miRNA decoys” or through competition for RNA-binding proteins, there is no evidence for RN7SL430P itself having such a role[2][3]. Currently, it is not considered a therapeutic target or biomarker by any major source[1][4][3].

Other names

RN7SL430PRNA, 7SL, cytoplasmic 430, pseudogene