Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 483, pseudogene (RN7SL483P)

Target
RN7SL483P
Molecular classification
Other, Pseudogene, Noncoding RNA
01

Overview

RN7SL483P is a pseudogene of the 7SL RNA family located on human chromosome 12 (position 94,515,476-94,515,760 on the forward strand)[6]. The 7SL RNA is the RNA component of the signal recognition particle (SRP), a ribonucleoprotein complex involved in targeting proteins to the endoplasmic reticulum during translation[3][5]. However, RN7SL483P does not encode a functional RNA; it is classified as a processed pseudogene, meaning it represents a nonfunctional copy of the ancestral 7SL RNA gene[1][7]. These types of pseudogenes are generally thought to arise from reverse-transcribed RNAs that reintegrate into the genome, lacking normal gene regulatory features and coding potential[4][7]. There is no evidence that RN7SL483P itself has a biological role, acts as a therapeutic target, or is involved in disease[1][6][7]. Some other RNA pseudogenes can play regulatory roles through acting as miRNA decoys or modulating parental gene expression, but no such function is described for RN7SL483P specifically[4].

Other names
RN7SL483P
02

Biological functions

None (pseudogene; no coding or direct regulatory function established)
03

Disease associations

Other (no established disease role; generally, pseudogenes like 7SL RNAs can potentially act as microRNA decoys, but no evidence for this specific pseudogene)

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