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RNA, U6 small nuclear 781, pseudogene (RNU6-781P) is a human pseudogene located on chromosome 12[1][5]. It is a nonfunctional genomic sequence resembling the U6 small nuclear RNA (snRNA) family, which is involved in the splicing of pre-mRNA as a component of the spliceosome[4]. Pseudogenes such as RNU6-781P have lost their ability to code for functional RNAs or proteins due to mutations or processing errors but may be transcribed at low levels; in some cases, pseudogenes can participate in regulatory RNA networks, but there is currently no evidence this specific pseudogene has such a function[2]. RNU6-781P has no established role in human disease, no known relevance as a therapeutic target, and no associated interacting drugs or biomarkers.
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