RNA, 18S ribosomal pseudogene

*RNA, 18S ribosomal pseudogene (ENSG00000225840)* is a **processed pseudogene** found on chromosome Y in humans, specifically at 10,197,256-10,199,103 on the reverse strand[1][5]. As a pseudogene, it is an inactive or non-functional copy of the gene responsible for 18S ribosomal RNA, a core component of the small ribosomal subunit involved in protein synthesis[1][9]. Unlike functional ribosomal RNA genes, this pseudogene does not produce a protein-coding product and is generally not transcribed to produce functional ribosomal RNA. \n Pseudogenes like this can sometimes be transcribed into noncoding RNA and may regulate related coding genes through mechanisms such as acting as microRNA decoys or generating small interfering RNAs involved in gene expression regulation[4][8]. However, there is no evidence that this specific pseudogene has a direct therapeutic, druggable, or receptor/enzyme role in disease. \n The gene is cataloged for genomic and evolutionary studies and serves as a marker for processed pseudogenes, but is **not a canonical therapeutic target** such as a receptor, enzyme, or transporter. Its assignment as a "target" is inappropriate for typical drug discovery or clinical biomarker contexts[1][10].

Other names

18S ribosomal pseudogeneENSG00000225840