RNA, 5S ribosomal pseudogene 130 (RNA5SP130)

RNA, 5S ribosomal pseudogene 130 (RNA5SP130) is a processed pseudogene that closely resembles the functional 5S ribosomal RNA gene but has accumulated mutations and lacks the regulatory elements required for transcription and function[3][6]. Pseudogenes like RNA5SP130 are common in the human genome and usually do not produce functional products[6]. They are remnants of evolutionary gene duplication or retrotransposition events and typically do not play roles in protein synthesis, cellular signaling, or disease[6]. This pseudogene itself is not considered a therapeutic target and does not interact with drugs, serve as a biomarker, or present safety concerns relevant to drug development[3][6]. RNA5SP130 shares sequence similarity with the 5S rRNA gene; however, unlike the functional 5S rRNA, which is a conserved component of the large ribosomal subunit involved in translation[1][7], RNA5SP130 does not encode an active RNA molecule and is classified as a non-coding, non-functional genomic element[3][6]. If you need information on the actual 5S ribosomal RNA itself, that is a bona fide structural RNA component of the ribosome, distinct from pseudogenes like RNA5SP130[1].

Other names

RN5S130RNA, 5S ribosomal 130RNA5SP130