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RNA, 5S ribosomal pseudogene 135 (RNA5SP135) is a human pseudogene related to 5S ribosomal RNA sequences. Pseudogenes of this type are non-functional DNA segments derived from ancestral gene duplication or retrotransposition events and do not code for functional RNA or protein products. 5S rRNA is normally an integral structural and functional component of the large ribosomal subunit and is required for ribosome assembly and function[1][3][7], but the 'pseudogene' designation indicates RNA5SP135 itself is not transcribed into a functional 5S rRNA molecule. As such, it is not classified as a therapeutic target and has no known associated biological function, drug interactions, or disease relevance. While some pseudogenes have been implicated as biomarkers or in gene regulation, there is no evidence indicating that RNA5SP135 has any such roles[2][5][6][10].
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