RNA, 5S ribosomal pseudogene 143 (RNA5SP143)

RNA, 5S ribosomal pseudogene 143 is categorized as a *pseudogene*—specifically, a non-functional genomic sequence related to the 5S ribosomal RNA gene family[1]. 5S rRNA is a structural component of the large ribosomal subunit, but pseudogenes such as RNA5SP143 do not produce active RNA molecules and generally lack biological function. While many ribosomal RNA pseudogenes exist in the human genome due to gene duplication and retrotransposition events, most are transcriptionally inactive and do not contribute to ribosomal function or cellular biology[1][3]. Some pseudogenes, in general, are implicated in gene regulation via miRNA competition (as ceRNAs), but there is no evidence RNA5SP143 itself has a regulatory or pathological role[4]. It is **not** considered a receptor, enzyme, or typical drug target. Summary of limitations: - RNA5SP143 is a pseudogene, not a functional gene or protein, and not a receptor or any conventional druggable target[1]. - There is no evidence to date of direct disease association or of utilization as a therapeutic biomarker. - No known drugs interact with or are designed to act through this sequence. - The biological importance of most individual ribosomal RNA pseudogenes, including RNA5SP143, remains undefined. If you require information on a functional 5S ribosomal RNA or its protein components (e.g., as a ribosome structural target), these are distinct entities from pseudogenes and could be discussed separately[3][5].

Other names

RN5S143RNA, 5S ribosomal 143RNA5SP143