RNA, 5S ribosomal pseudogene 166 (RNA5SP166)

RNA, 5S ribosomal pseudogene 166 (RNA5SP166) is a human **processed pseudogene** derived from the 5S ribosomal RNA gene[2][4]. Unlike functional 5S rRNA genes, pseudogenes like RNA5SP166 do not encode functional RNA products due to mutations or lack of necessary regulatory elements[4]. They are considered "processed" because they arise via retrotransposition and typically lack introns and regulatory sequences of the original gene[4]. While 5S rRNA itself is an essential part of the ribosome with structural and regulatory roles in protein synthesis[1][3][5], pseudogenes such as RNA5SP166 have no direct biological function and are **not recognized therapeutic targets**[2][4]. However, the expression of some pseudogenes can be associated with certain disease states, including cancer, where their RNA levels may be used as novel biomarkers to stratify subtypes or predict outcomes[6]. RNA5SP166, specifically, has no documented direct involvement in drug targeting or disease mechanisms and is not considered a functionally relevant molecule.\n\nKey notes:\n- This entry is a *pseudogene* and **not** a protein, enzyme, receptor, or RNA molecule with cellular activity.\n- Its classification as a *target* is incorrect; it is not used as a therapeutic or diagnostic target.\n- Its main relevance, if any, comes from its use in global transcriptomics as a biomarker rather than as a functional molecule or drug target[6].

Other names

RNA5SP166RN5S166RNA, 5S ribosomal 166RNA, 5S ribosomal pseudogene 166