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RNA, 5S ribosomal pseudogene 183 is a pseudogene, meaning it closely resembles a real gene (5S ribosomal RNA gene), but is generally considered non-functional and not transcribed or translated in a way that contributes directly to cell biology[2][6]. 5S ribosomal RNA is a highly conserved, ~120 nucleotide RNA that forms part of the large ribosomal subunit and plays structural and potentially regulatory roles in ribosome function and assembly[1][5][7]. Pseudogenes like RNA5SP183 typically arise through gene duplication or retrotransposition and accumulate mutations preventing normal function[6]. While some pseudogenes can have regulatory roles or serve as cancer biomarkers when taken as a group, there is no specific evidence that RNA, 5S ribosomal pseudogene 183 alone is a therapeutic target, disease gene, or biomarker[2][4].\n- Pseudogenes are generally not themselves receptors, enzymes, or functional protein-coding targets, though global pseudogene expression analysis may reveal clinical associations in certain cancers[4].\n- RNA, 5S ribosomal pseudogene 183 is correctly classified as a pseudogene, not an actionable molecular target[2][6].
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