RNA, 5S ribosomal pseudogene 285 (RNA5SP285)

RNA, 5S ribosomal pseudogene 285 (RNA5SP285) is a processed pseudogene in the human genome that is homologous to functional 5S ribosomal RNA (rRNA) genes. While functional 5S rRNA is a small, highly conserved RNA component of the large ribosomal subunit critical for protein synthesis[1][3][5][7], the RNA5SP285 locus does not produce a functional 5S rRNA and is transcriptionally inactive or only very rarely transcribed as a non-coding RNA with no established function[2]. Pseudogenes like RNA5SP285 can sometimes be transcribed and, in rare cases, may play regulatory roles or serve as sources of small RNAs, but there is no evidence that RNA5SP285 has such activity in humans[4][8]. It is not a therapeutic target, enzyme, receptor, transporter, or any other classical drug target. The locus is mainly of interest in evolutionary and genomic studies as part of the rich repertoire of ribosomal gene pseudogenes found in eukaryotic genomes[2][3][7]. Key points: - This is **not a functional gene or protein/receptor** and is **not a current or potential therapeutic target**. - Its inclusion in drug target lists is an error or the result of automated annotation pipelines. - Pseudogenes like RNA5SP285 are generally considered **non-functional**; in some cases, pseudogenes can modestly influence gene regulation, but this is not established for this locus.

Other names

RN5S285RNA5SP285RNA, 5S ribosomal 285