Target intelligence / Profile preview

RNA, 5S ribosomal pseudogene 353 (RNA5SP353)

Target
RNA5SP353
Molecular classification
Other (Pseudogene)
01

Overview

RNA, 5S ribosomal pseudogene 353 (RNA5SP353), is classified as a processed pseudogene derived from the functional 5S ribosomal RNA gene[2][4][6][7]. 5S ribosomal RNA is a critical structural component of the large ribosomal subunit involved in protein synthesis[1][3][5], but RNA5SP353 lacks protein-coding potential and is not transcribed into a functional product. As a processed pseudogene, it is the result of reverse transcription and genomic integration of a 5S rRNA transcript, typically lacking regulatory elements for active expression[6]. Pseudogenes as a class may have roles as competitive endogenous RNAs, but there is no direct evidence that RNA5SP353 plays such a role. It is not considered a therapeutic or diagnostic target.

Other names
RN5S353RNA, 5S ribosomal 353RNA5SP353
02

Biological functions

None (as a pseudogene, presumed non-functional at the molecular level, although general pseudogene effects like regulatory RNA could be possible)
03

Disease associations

Other (no direct evidence for involvement in disease; some studies describe pseudogene expression as correlating with cancer subtypes, but not this specific gene)

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