RNA, 5S ribosomal pseudogene 378 (RNA5SP378)

RNA, 5S ribosomal pseudogene 378 (RNA5SP378) is classified as a **pseudogene** in the human genome, derived from ancestral duplication events of the 5S ribosomal RNA (rRNA) gene[1][2]. Pseudogenes are DNA sequences similar to normal genes but typically non-functional due to mutations or lack of regulatory elements required for normal gene expression[6][8]. The 5S rRNA genes normally encode an essential RNA component of the large ribosomal subunit central to protein synthesis[3][5], but RNA5SP378 itself does not code for a functional product[1][2]. Current evidence does not link this particular pseudogene to disease, drug interactions, or classic molecular functions beyond potential roles in non-coding RNA-mediated regulation, a feature described for some transcribed pseudogenes in the general biomedical literature[6]. There are no known biomarkers or safety concerns associated with RNA5SP378.

Other names

RN5S378RNA5SP378RNA, 5S ribosomal 378