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RNA, 5S ribosomal pseudogene 465 is a human pseudogene, a non-coding genomic DNA sequence resembling the functional 5S ribosomal RNA gene. Pseudogenes like RNA5SP465 result from gene duplication or retrotransposition events and typically accumulate mutations over time, rendering them nonfunctional[8]. While some pseudogenes can be transcribed and exert biological activity (such as acting as microRNA decoys or regulatory RNAs[2]), there is no specific evidence for any functional or disease role associated with RNA5SP465. It should not be considered a relevant therapeutic target, disease biomarker, or a protein-encoding gene. Its primary classification is as a ribosomal RNA pseudogene, and it nominally belongs to the non-coding RNA family.
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