RNA, 7SK small nuclear pseudogene 9 (RN7SKP9)

RN7SK pseudogene 9 (RN7SKP9) is a genomic sequence annotated as a pseudogene of the RNA, 7SK small nuclear RNA (RN7SK). RN7SK itself is a highly conserved, ubiquitously expressed small nuclear noncoding RNA transcribed by RNA polymerase III, which acts as a scaffold for the 7SK small nuclear ribonucleoprotein (snRNP) complex, regulating transcription elongation by RNA polymerase II through its interaction with P-TEFb and other factors[1][2][3][4]. RN7SK plays functional roles in cell differentiation, proliferation, and senescence and is involved in innate immune functions, particularly in macrophage polarization and phagocytosis[1][2][4]. However, RN7SKP9 refers specifically to a *pseudogene*—a non-functional copy of the RN7SK gene—with no established biological activity, disease relevance, or drug interactions. There is currently no evidence that RN7SKP9 codes for a functional RNA, protein, or acts as a molecular target in therapy or research. Key points: - All functional and biological data in the literature relate to RN7SK, not RN7SKP9[1][2][3][4]. - RN7SKP9 does not encode a regulatory RNA and is not considered a molecular target for drugs, biomarkers, or disease processes. - It is sometimes incorrectly listed in target databases due to its similarity in nomenclature to RN7SK. If a functional or disease role is required for research or therapeutic targeting, refer to the canonical "RNA, 7SK small nuclear RNA" (RN7SK), not RN7SKP9.

Other names

RN7SKP9RNA, 7SK small nuclear pseudogene 97SK small nuclear RNA pseudogene 9