Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 176, pseudogene (RN7SL176P)

Target: RN7SL176P
Molecular classification: Non-coding RNA, Pseudogene, Other

Overview

RN7SL176P is a genomic pseudogene corresponding to the RNA, 7SL, cytoplasmic family. It is a non-coding sequence derived via retrotransposition from the 7SL RNA gene, which encodes the RNA component of the signal recognition particle (SRP) and mediates cotranslational targeting of proteins to the endoplasmic reticulum. However, RN7SL176P contains truncations and mutations typical of processed pseudogenes, meaning it is not expressed or functional in the cell. Human genomic DNA contains hundreds of such 7SL RNA pseudogene copies[7]. These pseudogenes do not participate in biological pathways or disease biology, do not encode proteins, do not interact with therapeutic agents, and have no recognized clinical or research utility as receptor or therapeutic targets.

Other names: RN7SL176P7SL pseudogeneRNA, 7SL, cytoplasmic 176, pseudogene

Mechanism of action

None. Drugs do not target this pseudogene, so there are no mechanisms of action available.

Biological functions

As a pseudogene, it does not encode a functional RNA or protein and does not play a known biological role in normal cell function. Functional 7SL RNA genes are involved in protein targeting via the signal recognition particle (SRP), but pseudogenes like RN7SL176P are non-functional copies.

Disease associations

Pseudogenes in the 7SL RNA family do not have established roles in disease, unlike the functional 7SL RNA gene which may be implicated in cancer or immune activation. RN7SL176P is not reported to act in disease contexts.

Safety considerations

The pseudogene status excludes it from therapeutic safety evaluations.

Interacting drugs

No molecular drugs are known to interact with this pseudogene or use it as a pharmacological target.

Biomarkers

RN7SL176P is not used as a biomarker for disease or therapy selection.

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