RNA, 7SL, cytoplasmic 231, pseudogene (RN7SL231P)

RN7SL231P (RNA, 7SL, cytoplasmic 231, pseudogene) is a pseudogene related to the 7SL RNA family. The functional 7SL RNA is a non-coding RNA component of the signal recognition particle (SRP) complex, which is essential for targeting secretory proteins to the endoplasmic reticulum in eukaryotic cells. However, RN7SL231P is a **pseudogene**—a non-functional genomic DNA sequence that resembles the 7SL RNA gene but does not produce a functional RNA or protein product. There are hundreds of 7SL RNA pseudogenes throughout the human genome, thought to have arisen by the reverse transcription of 7SL RNA and reintegration into the genome, but only a small number (about four) encode functional 7SL RNA[1][4]. RN7SL231P is not known to be expressed, has no established biological function, is not implicated in disease, and is not a therapeutic target. Key context and supporting details: - Pseudogenes such as RN7SL231P are **non-coding, non-functional copies** of genes and generally considered genomic relics without direct functional significance[1]. - The true biological target of interest in the 7SL family is the **functional 7SL RNA**, or RN7SL1, which is essential for the **signal recognition particle (SRP)**, a critical ribonucleoprotein complex in the secretory pathway[5][6]. - The signal recognition particle RNA has canonical roles in cotranslational targeting of proteins to the endoplasmic reticulum, but **pseudogenes do not perform that function**. - There are no drugs, disease associations, or biomarker uses for RN7SL231P; these are properties attributed to functional genes, not pseudogenes[4].

Other names

RN7SL231P7SL RNA pseudogene