RNA, 7SL, cytoplasmic 233, pseudogene (RN7SL233P)

RN7SL233P is a human pseudogene related to the functional 7SL RNA, which is a central non-coding RNA component of the signal recognition particle (SRP) ribonucleoprotein complex[1][5][3][7]. The functional 7SL RNA directs the co-translational insertion of secretory and membrane proteins into the endoplasmic reticulum, but RN7SL233P is a truncated, non-functional copy that arose via retrotransposition events[5]. Pseudogenes like RN7SL233P usually display high sequence similarity to their functional counterparts but typically lack regulatory elements or proper transcription resulting in a lack of biological activity[1][5][6]. Most 7SL-derived pseudogenes are not transcribed or translated, have no direct functional product, and are not considered therapeutic targets or involved in disease processes, though the larger family of pseudogenes can impact gene regulation indirectly in rare circumstances[4][1].

Other names

RN7SL233PRNA, 7SL, cytoplasmic 233, pseudogene