RNA, 7SL, cytoplasmic 258, pseudogene (RN7SL258P)

RN7SL258P is a human pseudogene sequence related to the 7SL RNA component of the signal recognition particle (SRP)[3][7][4]. The original 7SL RNA acts as a scaffold within the SRP, which mediates co-translational targeting of nascent secretory and membrane proteins to the endoplasmic reticulum[1][5]. The RN7SL258P locus reflects a non-functional, non-coding remnant of this system, generated through reverse transcription and integration back into the genome as a defective or truncated version of the original gene[3]. Pseudogenes, including RN7SL258P, are typically considered "genomic fossils" but may under some circumstances have regulatory functions—such as involvement in RNA interference or as microRNA sponges. However, no specific biological function or disease association has been reported for RN7SL258P[6][7]. RN7SL pseudogenes are numerous in the human genome and are commonly associated with Alu repeat elements[1][3]. There is no evidence that RN7SL258P is involved in any pharmacological mechanism, nor does it serve as a biomarker or therapeutic target. Summary: RN7SL258P is a human non-coding pseudogene related to 7SL RNA. It is not considered a therapeutic target, has no established biological function or disease role, and is not actionable by known drugs[3][6][7].

Other names

RN7SL258PRNA, 7SL, cytoplasmic 258, pseudogeneHGNC: 46274NCBI Gene: 106480373Ensembl: ENSG00000240589

Not applicable; does not serve as a drug target