RNA, 7SL, cytoplasmic 357, pseudogene (RN7SL357P)

**RN7SL357P** is a human pseudogene derived from the gene encoding 7SL RNA, the non-protein-coding RNA component of the signal recognition particle (SRP) complex[1][2]. The majority of 7SL-family pseudogenes, including RN7SL357P, are the result of retrotransposition events and do not code for functional RNAs or proteins[2][1]. Unlike the canonical 7SL RNA gene—which plays a crucial role in the recognition and targeting of proteins to the endoplasmic reticulum membrane—RN7SL357P is considered non-functional and is not expressed at appreciable levels in human cells[1][2]. There is no evidence to suggest that RN7SL357P acts as a therapeutic target, is involved in disease, encodes a receptor, or interacts with any known drugs[1][2]. **Key clarifications:** - RN7SL357P is a *pseudogene*, not a protein-coding gene, receptor, or a targetable biological molecule. - The canonical functional molecule in this family is **7SL RNA**, part of the signal recognition particle, but RN7SL357P itself is not involved in SRP function[1][2][5]. - There is no published evidence for disease association, biomarker status, or drug interaction involving this pseudogene[1]. **Summary:** RN7SL357P represents a non-functional, pseudogene copy of the 7SL RNA gene, lacking known biological function, disease relevance, or suitability as a druggable target[1][2].

Other names

RN7SL357PRNA, 7SL, cytoplasmic 357, pseudogene