RNA, 7SL, cytoplasmic 369, pseudogene (RN7SL369P)

RNA, 7SL, cytoplasmic 369, pseudogene (RN7SL369P) is a truncated, non-functional copy of the 7SL RNA gene. The 7SL RNA is a component of the signal recognition particle (SRP), which plays a key role in targeting secretory proteins to the endoplasmic reticulum[5]. RN7SL369P belongs to the large group of 7SL pseudogenes present in the human genome, believed to result from retrotransposition events—where the functional 7SL RNA transcript is reverse transcribed and integrated back into genomic DNA[3][4][6]. These pseudogenes are generally truncated at either end and lack promoters, rendering them nonfunctional “junk DNA”[2][3][4]. While some pseudogene transcripts may occasionally exert regulatory effects, RN7SL369P specifically has not been ascribed any such function in genetic, biochemical, or pharmacological contexts.\n\nNote:\n- The inclusion of RN7SL369P as a drug target is incorrect; pseudogenes are generally not suitable therapeutic targets, do not encode active proteins, and are not currently known to play a direct, essential role in human disease or therapy[2].\n- If you are seeking information about the functional 7SL RNA, that molecule (not the pseudogene) is part of the signal recognition particle RNA, which enables protein targeting to the ER[5].\n\nIf you need information about the canonical 7SL RNA gene, search for “RN7SL1,” “RN7SL2,” or “RN7SL3,” which are the three functional human SRP RNA genes[5]. RN7SL369P is just one among the hundreds of processed, non-functional 7SL RNA pseudogenes in the genome[3][4][6].

Other names

RN7SL369P7SL pseudogene7SL RNA pseudogene

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