RNA, 7SL, cytoplasmic 446, pseudogene (RN7SL446P)

**RN7SL446P**—also known as RNA, 7SL, cytoplasmic 446, pseudogene—is a member of the large family of 7SL RNA pseudogenes found in the human genome. The 7SL RNA is the RNA component of the signal recognition particle (SRP), a ribonucleoprotein complex essential for directing proteins to the endoplasmic reticulum. However, **RN7SL446P** itself is classified as a **pseudogene**: it is a non-functional genomic sequence similar to the functional 7SL RNA gene, but it does not produce an active product required for SRP function and is not known to act directly as a therapeutic or biological target[1][5][6][8]. Most 7SL RNA pseudogenes, including RN7SL446P, are truncated and dispersed copies of the functional 7SL RNA gene, likely created by reverse transcription and reintegration into the genome, and are not expressed at detectable levels or functional in known pathways[5][8]. While some pseudogenes in general have been described as sources of regulatory RNAs or as competitive endogenous RNAs, there is no evidence that **RN7SL446P** plays such roles or is clinically relevant for disease, drug action, or biomarker use[2][4]. The gene is annotated as “misc RNA” in genomic databases, reflecting its non-coding, non-functional nature[6].

Other names

RN7SL446PRNA, 7SL, cytoplasmic 446, pseudogene