RNA, 7SL, cytoplasmic 465, pseudogene (RN7SL465P)

RNA, 7SL, cytoplasmic 465, pseudogene (RN7SL465P) is a non-protein-coding pseudogene locus in the human genome, derived from the 7SL RNA. The 7SL RNA is an essential component of the signal recognition particle (SRP), which directs the traffic of proteins within cells, but RN7SL465P itself is a truncated, nonfunctional relic that does not encode a functional product. The vast majority of 7SL-derived loci in the human genome are pseudogenes generated by retrotranspositional events, where the RNA was reverse transcribed and reinserted into DNA, resulting in inactive copies[5][7][1]. While pseudogenes in general can have regulatory roles in rare cases (such as competing for microRNAs or influencing parental gene expression), there is no evidence that RN7SL465P specifically acts as a regulatory molecule or has an established role in disease biology or drug interaction[1][5][7][6]. **Key Points** - RN7SL465P is a **pseudogene**—a nonfunctional copy—not a receptor, enzyme, or other canonical drug target[1][5][7]. - It does not encode a protein, nor is it implicated as a biomarker, drug target, or therapeutic safety concern. - Like other pseudogenes, the locus is generally regarded as genomic background with very limited, if any, biological function. If a functional role for this or similar pseudogenes emerges in the future, it would most likely involve gene regulation at the RNA level, but such a function is not established for RN7SL465P[5][7][6].

Other names

RN7SL465P7SL RNA pseudogene