Target intelligence / Profile preview

RNA, 7SL, cytoplasmic 482, pseudogene (RN7SL482P)

Target
RN7SL482P
Molecular classification
Other (Non-coding RNA pseudogene)
01

Overview

**RNA, 7SL, cytoplasmic 482, pseudogene** (RN7SL482P) is a pseudogene corresponding to the 7SL RNA gene, which is normally a component of the signal recognition particle (SRP) complex involved in targeting secretory proteins to the endoplasmic reticulum[1][5][6]. Pseudogenes like RN7SL482P are typically nonfunctional genomic sequences that closely resemble functional genes but have accumulated mutations that prevent their normal function[6]. There are hundreds of such 7SL RNA-related pseudogenes in the human genome, but very few code for active RNA[5][6]. RN7SL482P itself does not encode an active product and does not participate in canonical molecular or disease pathways, nor is it considered a therapeutic target[1][5][6]. **Context:** - **Not a receptor, enzyme, or druggable target.** RN7SL482P is classified as a non-coding RNA pseudogene and not as a receptor, enzyme, transporter, or other molecular target relevant for pharmacological intervention[1][6]. - **Inaccurate as a drug discovery target.** There is no evidence in the literature that RN7SL482P encodes a functional molecule or that it is implicated in human disease mechanisms, drug interaction, or use as a biomarker[1][5][6]. - **Potential confusion:** The name is accurate as a pseudogene, but using it as a target for therapy, biomarker, or mechanism of action is incorrect; thus, for most drug databases, this entry would be considered erroneous or out of scope for therapeutic targeting[1][5][6]. **Summary of inaccuracies:** RN7SL482P is not an actual molecular target in the sense required for drug action, pathology, or biomarker use. It is one of many nonfunctional 7SL RNA-derived pseudogenes, not associated with protein production or physiological regulation in humans[5][6].

Other names
RN7SL482P

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