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RNA, 7SL, cytoplasmic 622, pseudogene (RN7SL622P)

Target: RN7SL622P
Molecular classification: Pseudogene, Non-coding RNA pseudogene [7][8]

Overview

RN7SL622P is a human pseudogene that represents a non-functional genomic sequence homologous to 7SL RNA, a component of the signal recognition particle (SRP). While functional 7SL RNA is essential for targeting secretory proteins to the endoplasmic reticulum, RN7SL622P does not code for a functional RNA or protein and is not expressed at a detectable level. The human genome contains hundreds of such 7SL pseudogenes, which are thought to arise via retrotransposition or similar processes and serve as molecular fossils. There is no evidence that RN7SL622P plays a direct role in health or disease or that it is targeted by any drugs or clinical biomarkers[5][7][8][9].

Other names: RN7SL622PRNA, 7SL, cytoplasmic 622, pseudogene [7][8]

Biological functions

No direct canonical function; as a pseudogene, it does not participate in biological processes typical of protein-coding genes.Pseudogenes can serve as sources of non-coding RNAs with potential regulatory functions such as acting as miRNA sponges or producing small interfering RNAs, but this is not demonstrated for every individual pseudogene, including RN7SL622P to current knowledge[2][6]

Disease associations

None specifically documented for RN7SL622P.In general, some pseudogenes may play roles in gene regulation related to diseases (such as acting as competitive endogenous RNAs in cancer)[2][6], but there is no evidence for RN7SL622P specifically

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