RNA, U1 small nuclear 105, pseudogene (RNU1-105P)

RNA, U1 small nuclear 105, pseudogene (RNU1-105P) is a human pseudogene corresponding to a U1 small nuclear RNA (snRNA) gene family member[1][4][6]. Pseudogenes such as RNU1-105P are derived from genes that encode functional RNAs but have accumulated mutations rendering them non-functional; thus, this locus does not yield a functional snRNA involved in spliceosomal activity. RNU1-105P lacks the biological activity of canonical U1 snRNA, which normally plays a role in pre-mRNA splicing as a component of the spliceosome. There are no known therapeutic interventions, disease associations, or use as a biomarker or drug target related to RNU1-105P[1][4][6]. **Clarification:** RNU1-105P is a *pseudogene*, not a protein-coding gene, not a receptor, and not a therapeutic target. Pseudogenes are generally *not* targets for drugs, do not have direct biological functions themselves, and are not involved as disease markers unless specified otherwise in the literature, which is not the case for RNU1-105P per available data[1][4][6]. **Summary of issues:** - RNU1-105P is not a true molecular target (e.g., receptor, enzyme, transporter); it is a non-coding RNA pseudogene[1][4][6]. - There is no evidence it has any therapeutic relevance, biological function, disease association, or drug interaction. - It should not be used as a canonical therapeutic target entry.

Other names

RNU1-105P