Target intelligence / Profile preview

RNA, U1 small nuclear 132, pseudogene (RNU1-132P)

Target: RNU1-132P
Molecular classification: Non-coding RNA, Small nuclear RNA pseudogene, Other

Overview

RNU1-132P (RNA, U1 small nuclear 132, pseudogene) is annotated as a pseudogene of the U1 small nuclear RNA (snRNA) family. U1 snRNAs are small non-coding RNAs fundamental for the splicing of pre-mRNA by recognizing the 5′ splice site and recruiting the spliceosome complex[1][3][5]. However, as a **pseudogene**, RNU1-132P is not believed to produce a functional RNA product or participate in splicing or any canonical pathway. Pseudogenes often arise via duplication or retrotransposition and lose their ability to code for functional RNA or proteins. There is no evidence that RNU1-132P acts as a receptor, enzyme, transporter, or any other conventional therapeutic target class. Although mutations and structural variation in canonical U1 snRNA loci have been linked to splicing alterations in cancer[4], no such association has been described for this specific pseudogene.

Other names: RNU1-132PRNA, U1 small nuclear 132, pseudogene

Biological functions

Other (Pseudogenes generally lack functional biological activity; canonical U1 snRNAs are involved in pre-mRNA splicing, but pseudogenes like RNU1-132P do not encode functional products)

Disease associations

Other (No direct disease association known for this pseudogene; U1 snRNA variants and mutations at related loci have been implicated in cancer and other diseases, but there is no evidence for RNU1-132P itself having a disease role[4])

Beyond the preview

Go deeper on RNA, U1 small nuclear 132, pseudogene (RNU1-132P).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on RNA, U1 small nuclear 132, pseudogene (RNU1-132P).

Explore the full profile