RNA, U1 small nuclear 57, pseudogene (RNU1-57P)

RNA, U1 small nuclear 57, pseudogene (RNU1-57P) is listed in human genome annotations as a pseudogene—specifically, a member of the non-coding small nuclear RNA U1 family, but without coding function[5]. Unlike canonical U1 snRNAs (such as RNU1-1), which are essential for accurate pre-mRNA splicing and transcriptome integrity, RNU1-57P does not produce a functional RNA and is not involved in splicing or transcriptional regulation[1][5]. Pseudogenes like RNU1-57P are remnants of genomic evolution and do not serve as direct molecular or therapeutic targets[5]. The entry is correctly abbreviated as RNU1-57P, matching the HGNC nomenclature[5]. Any reference to U1 snRNA biological functions pertains to active, non-pseudogene family members (e.g., RNU1-1), not RNU1-57P[1][5]. It is not a receptor, enzyme, transporter, or any other pharmacologically actionable target. There is no evidence of this locus being implicated in disease or targeted by drugs. All major databases, including GeneCards and HGNC, consistently classify RNU1-57P as a pseudogene with no known function, clinical relevance, or drug interactions[5].

Other names

RNA, U1 Small Nuclear 57, PseudogeneRNU1-57P