RNA, U1 small nuclear 84, pseudogene (RNU1-84P)

RNU1-84P (RNA, U1 small nuclear 84, pseudogene) is a human gene annotated as a pseudogene corresponding to the U1 small nuclear RNA family. It is not a protein-coding gene, nor is it known to produce a functional noncoding RNA molecule or to act as a direct therapeutic target in biomedical research[2][4][6].\nRNU1-84P (RNA, U1 small nuclear 84, pseudogene) is a human pseudogene located on chromosome 11q13.2[5]. It is classified as a U1 small nuclear RNA–related pseudogene, which means it is a nonfunctional genomic element that resembles the gene encoding U1 snRNA but does not produce a biologically active transcript or protein[2][4][6]. The canonical U1 snRNA is an essential component of the spliceosome, involved in pre-mRNA splicing and regulation of transcriptome integrity[1][7]. However, RNU1-84P lacks the ability to contribute to these functions and is not considered a therapeutic or diagnostic target.\nThere is no evidence that RNU1-84P itself plays any role in cell signaling, disease, or therapeutic mechanisms. Its only significance is in genome annotation, helping distinguish functional genes from nonfunctional genomic sequences.\nIf you are searching for a therapeutic target related to U1 small nuclear RNA, the correct entry would be the functional gene (such as RNU1-1, encoding U1 snRNA), not the pseudogene RNU1-84P[1][7].

Other names

HGNC:48426NCBI Gene: 106481618Ensembl: ENSG00000202317

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