RNA, U2 small nuclear 23, pseudogene (RNU2-23P)

RNU2-23P (RNA, U2 small nuclear 23, pseudogene) is a human pseudogene of the U2 small nuclear RNA (snRNA) family. Pseudogenes like RNU2-23P do not produce functional RNA and are considered noncoding genomic elements. Unlike functional U2 snRNA genes (such as RNU2-1 or RNU2-2), which are integral to the major spliceosome's role in pre-mRNA splicing, pseudogenes such as RNU2-23P are not expressed or biologically functional. Recent advances have clarified that previously annotated U2 pseudogenes (like RNU2-2P, now recognized as RNU2-2) can sometimes have biological roles; however, there is no evidence that RNU2-23P functions as either a gene product or a therapeutic target[1][2][3]. Key Notes: - The designation “pseudogene” denotes that RNU2-23P does not code for a functional molecule and has no known physiological or pathological relevance[2][3]. - Misidentification is possible in literature because other U2-related snRNA genes (such as RNU2-2, previously labeled as RNU2-2P) have recently been shown to have functional consequences, but this does **not** apply to RNU2-23P[2]. - RNU2-23P is not a drug target, receptor, enzyme, or actionable biomolecule. It is best described as a nonfunctional genomic element. If you are seeking information about a functionally relevant U2 snRNA gene, consider RNU2-1 or RNU2-2—the latter was previously (incorrectly) annotated as a pseudogene ("RNU2-2P") but is now established as a functional gene with disease relevance[2]. RNU2-23P, the specific subject of your query, does not meet criteria for a therapeutic, diagnostic, or functional molecular target.

Other names

RNU2-23PU2 snRNA pseudogene 23RNA, U2 small nuclear pseudogene 23

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